RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-29b-1
RNA ID
RNA Type
miRNA
Alteration Pattern
dna methylation
Species
homo sapiens
Detection Methods
RT-PCR; etc.
Target
PTEN
Pathway
ERK; PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
HOTAIR Epigenetically Modulates PTEN Expression via MicroRNA-29b: A Novel Mechanism in Regulation of Liver Fibrosis
Year
2017
Function
A histone deacetylase-4-dependent mechanism underlies the epigenetic silencing of mmp genes during tissue fibrogenesis.